Sharon Rose Pfeiffer has concertized extensively throughout the United States and Europe, including organ solos, recitals and radio broadcasts in New York City, at the National Cathedral in Washington, D.C., at Westminster Choir College in Princeton, NJ, and Wheaton College in Illinois. The winner of a Fulbright scholarship, Pfeiffer spent a year in Toulouse, coaching with the late composer and organist Xavier Darasse, and researching organ restorations in southern France. During that year, she won first prize in the prestigious Concours Internationale des Arts Renaissance. In 1989, the French government sponsored Pfeiffer on a concert tour of southern France, where one reviewer described her playing as "exuberant...profoundly sensitive" La Depeche.

As a distinguished harpsichordist, Pfeiffer has performed with the Phoenix Chamber Orchestra, Phoenix Bach Choir, the Kansas City Chamber Orchestra, and the American Embassy in Paris.

Pfeiffer began her career as a church musician at the age of 13. She has served as organist/choirmaster for several major churches, implementing and developing extensive choir programs. Currently, she is an Artist-in-Residence for Gloriæ Dei Artes Foundation.

Pfeiffer received her Bachelor of Music degree from Westminster Choir College in Princeton, New Jersey, summa cum laude. She earned her Masters Degree and Doctorate in organ performance at the Eastman School of Music in Rochester, New York, where she was teaching assistant to David Craighead in organ and to Arthur Haas in harpsichord. During her time in Rochester, she was also Instructor of Organ and Harpsichord at Nazareth College, and Music Consultant for the Episcopal Diocese of Rochester. She resides in Orleans, Massachusetts with her husband and two children.